Matrix Hub and Spoke System for Opioid Treatment

In response to the opioid epidemic, Substance Abuse and Mental Health Services Administration (SAMHSA) and the California Department of Health Care Services (DHCS) have provided funding to tackle the opioid crisis using a model that has shown success in other states. The Hub and Spoke System in California will be a network of 19 hubs, each with their own spokes. California has boldly set a goal to provide treatment for 20,000 additional people over the next two years.

Matrix Institute is one of the 19 grantees and one of the two organizations provided grants in LA County (the other being Tarzana Treatment Center). Matrix is working with its partners, Venice Family Clinic, St. John’s Well Child and Family Center, and CLARE Foundation to provide an expanded network of medication-assisted treatment (MAT) and support for clinicians using MAT to treat opioid use disorders.

For more information about the Hub and Spoke Project, visit the California HSS Website.

Matrix hub and Spoke Opioid Treatment



Free and confidential consultation for clinicians from the Clinician Consultation Center at San Francisco General Hospital focusing on substance abuse in primary care.

6 am – 5pm PT Monday – Friday

Call (855) 300-3595 or submit cases online:

Objectives of the Substance Use Warmline:

  • Support primary care providers in managing complex patients with addiction, chronic pain, and behavioral health issues
  • Improve the safety of medication regimens to decrease the risk of overdose
  • Enhance the treatment, care and support for people living with or at risk for HIV
  • Discuss useful strategies for clinicians in managing their patients living with substance use, addiction and chronic pain. Consultation topics include:
    • Assessment and treatment of opioid, alcohol, and other substance use disorders
    • Approaches to suspected misuse, abuse, or diversion of prescribed opioids
    • Methods to simplify opioid-based pain regimens to reduce risk of misuse and toxicity
    • Urine toxicology testing- when to use it and what it means
    • Use of buprenorphine and the role of methadone maintenance
    • Withdrawal management for opioids, alcohol, and other CNS depressants
    • Harm reduction strategies and overdose prevention
    • Managing substance use in special populations (pregnancy, HIV, hepatitis)
    • Productive ways of discussing (known or suspected) addiction with patients.


The VSee platform allows for a HIPAA and 42 CFR-complaint chat among providers in our network.